GLCCI1

Across TCGA cell cohorts, GLCCI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,815 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GLCCI1-associated GO terms across cancer lineages are Chromosomal 5-methylcytosine DNA demethylation pathway, Meiotic telomere tethering at nuclear periphery, and Meiotic telomere clustering. Each is linked with GLCCI1 in more than 10 cancer types. Because this analysis shows association rather than direction, both GLCCI1-to-partner and partner-to-GLCCI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosomal 5-methylcytosine DNA demethylation pathway grouped by GLCCI1-low versus GLCCI1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLCCI1→partner) and Y-score (partner→GLCCI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.234	+1.849	.001	<.001	3	11
BLOOD_Leukemia	Meiotic telomere tethering at nuclear periphery →	+0.086	+0.938	.001	<.001	3	11
BLOOD_Leukemia	Meiotic telomere clustering →	+0.086	+0.938	.001	<.001	3	11
BLOOD_Leukemia	Meiotic attachment of telomere to nuclear envelope →	+0.086	+0.938	.001	<.001	3	11
STOMACH	Regulation of RNA export from nucleus →	+0.128	+1.831	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.069	+1.370	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,815 associations by consensus.

Chromosomal 5-methylcytosine DNA demethylation pathway by GLCCI1 expression — STOMACH

Explore this box plot interactively →