GLB1L3

Across TCGA cell cohorts, GLB1L3 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GLB1L3-associated genes across cancer lineages are TSHB, NLGN4Y, and TRIML1. Each is linked with GLB1L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLB1L3-to-partner and partner-to-GLB1L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSHB grouped by GLB1L3-low versus GLB1L3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLB1L3→partner) and Y-score (partner→GLB1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TSHB →	+0.070	+3.604	<.001	.004	3	1
LUNG_NSCLC_LUAD	NLGN4Y →	+1.120	+3.717	.002	.005	3	1
LUNG_NSCLC_LUAD	TRIML1 →	+0.084	+3.786	.001	.001	3	1
LUNG_NSCLC_LUAD	OR8B4 →	+0.027	+3.887	<.001	.002	3	1
STOMACH	OR3A1 →	+0.070	+4.285	<.001	.007	3	1
STOMACH	FTMT →	+0.050	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

TSHB by GLB1L3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →