GK5

Across TCGA patient cohorts, GK5 protein abundance is significantly associated with the RNA expression of many other genes, with 3,936 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GK5-associated genes across cancer lineages are COPS7A, PEX7, and RFTN1. Each is linked with GK5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GK5-to-partner and partner-to-GK5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GK5 versus COPS7A in PDAC, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GK5→partner) and Y-score (partner→GK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	COPS7A →	-0.612	-0.572	<.001	.002	3	2
LSCC	PEX7 →	+0.383	+0.403	.003	.009	3	2
LSCC	RFTN1 →	-0.556	-0.809	.003	<.001	3	2
PDAC	WNK2 →	+1.441	+0.693	.002	<.001	3	2
UCEC	FHL1 →	-1.424	-0.609	.004	.001	3	2
LSCC	TRAJ43 →	-1.075	-0.489	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,936 associations by consensus.

GK5 vs COPS7A — PDAC

Explore this scatter interactively →