GK5

Across TCGA cell cohorts, GK5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,626 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GK5-associated GO terms across cancer lineages are Glycerol-3-phosphate biosynthetic process, Cytosolic transport, and Vacuolar transport. Each is linked with GK5 in more than 17 cancer types. Because this analysis shows association rather than direction, both GK5-to-partner and partner-to-GK5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycerol-3-phosphate biosynthetic process grouped by GK5-low versus GK5-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GK5→partner) and Y-score (partner→GK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Glycerol-3-phosphate biosynthetic process →	+1.265	+0.736	<.001	<.001	3	18
LARGE_INTESTINE	Cytosolic transport →	+0.061	+0.681	<.001	.001	3	15
URINARY_TRACT	Vacuolar transport →	+0.052	+1.080	.001	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to vacuole →	+0.074	+0.836	.001	.001	3	14
SKIN	Vesicle-mediated transport to the plasma membrane →	+0.043	+0.579	.003	<.001	3	14
PANCREAS	Negative regulation of macroautophagy →	+0.076	+0.731	.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,626 associations by consensus.

Glycerol-3-phosphate biosynthetic process by GK5 expression — PANCREAS

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