GK5

Across TCGA cell cohorts, GK5 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GK5-associated genes across cancer lineages are WFDC11 and CNGA2. Each is linked with GK5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GK5-to-partner and partner-to-GK5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WFDC11 grouped by GK5-low versus GK5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GK5→partner) and Y-score (partner→GK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	WFDC11 →	+0.041	+5.539	<.001	.003	3	1
BLOOD_Leukemia	CNGA2 →	+0.099	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

WFDC11 by GK5 expression — BLOOD_Leukemia

Explore this box plot interactively →