GK4P

Across TCGA patient cohorts, GK4P RNA expression is significantly associated with the go_rna of many other GO terms, with 7,153 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible GK4P-associated GO terms across cancer lineages are COPII-coated vesicle cargo loading, Vesicle cargo loading, and Phosphatidylinositol-3-phosphate biosynthetic process. Each is linked with GK4P in more than 30 cancer types. Because this analysis shows association rather than direction, both GK4P-to-partner and partner-to-GK4P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle cargo loading grouped by GK4P-low versus GK4P-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GK4P→partner) and Y-score (partner→GK4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	COPII-coated vesicle cargo loading →	+0.103	+0.296	<.001	<.001	3	31
DLBC	Vesicle cargo loading →	+0.070	+0.742	<.001	<.001	3	30
DLBC	Phosphatidylinositol-3-phosphate biosynthetic process →	+0.087	+0.668	<.001	<.001	3	30
DLBC	Regulation of autophagosome assembly →	+0.055	+0.682	<.001	<.001	3	30
DLBC	Negative regulation of macroautophagy →	+0.080	+0.786	<.001	<.001	3	29
DLBC	Protein localization to Golgi apparatus →	+0.053	+0.671	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,153 associations by consensus.

COPII-coated vesicle cargo loading by GK4P expression — UCS

Explore this box plot interactively →