Across TCGA patient cohorts, GK RNA expression is significantly associated with the protein abundance of many other proteins, with 13,723 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GK-associated proteins across cancer lineages are MNDA, MYO1F, and NCF2. Each is linked with GK in more than 7 cancer types. Because this analysis shows association rather than direction, both GK-to-partner and partner-to-GK results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GK→partner) and Y-score (partner→GK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MNDA →	+0.938	+0.524	<.001	<.001	3	8
GBM	MYO1F →	+0.545	+0.591	<.001	<.001	3	8
GBM	NCF2 →	+0.756	+0.535	<.001	<.001	3	8
GBM	FMNL1 →	+0.565	+0.608	<.001	<.001	3	8
COAD	PRAM1 →	+0.750	+0.795	.002	.001	3	7
LSCC	PRAM1_S298 →	+0.982	+0.630	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,723 associations by consensus.

Exploration

GK survival (RNA) · tumor vs normal (RNA) · all GK data types