Across TCGA patient cohorts, GK protein abundance is significantly associated with the RNA expression of many other genes, with 6,824 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GK-associated genes across cancer lineages are MPP1, GK-AS1, and SLA2. Each is linked with GK in more than 3 cancer types. Because this analysis shows association rather than direction, both GK-to-partner and partner-to-GK results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GK→partner) and Y-score (partner→GK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MPP1 →	+0.955	+0.447	<.001	<.001	3	4
LUAD	GK-AS1 →	+0.895	+0.588	<.001	<.001	3	4
UCEC	SLA2 →	+0.842	+0.476	<.001	.004	3	4
BRCA	IL4I1 →	+0.985	+0.307	.001	.005	3	4
CCRCC	LILRB5 →	+0.885	+0.410	<.001	<.001	3	4
UCEC	FASLG →	+1.120	+0.496	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,824 associations by consensus.

Exploration

GK survival (RNA) · tumor vs normal (RNA) · all GK data types