GJA9

Across TCGA cell cohorts, GJA9 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GJA9-associated genes across cancer lineages are STXBP3, RNF19B, and CTH. Each is linked with GJA9 in more than 1 cancer types. Because this analysis shows association rather than direction, both GJA9-to-partner and partner-to-GJA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STXBP3 grouped by GJA9-low versus GJA9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA9→partner) and Y-score (partner→GJA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	STXBP3 →	+0.526	+3.067	.001	.009	3	1
LARGE_INTESTINE	RNF19B →	+0.718	+3.064	.007	.009	3	1
LARGE_INTESTINE	CTH →	+1.034	+3.364	.008	.002	3	1
LARGE_INTESTINE	ATP8A1 →	+1.119	+3.364	.008	.002	3	1
LARGE_INTESTINE	ALKBH7 →	+0.518	+3.364	<.001	.002	3	1
LARGE_INTESTINE	GPBP1L1 →	+0.463	+3.364	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

STXBP3 by GJA9 expression — LARGE_INTESTINE

Explore this box plot interactively →