GJA8

Across TCGA patient cohorts, GJA8 protein abundance is significantly associated with the RNA expression of many other genes, with 5,541 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GJA8-associated genes across cancer lineages are TCEA3, PEAK3, and PLPPR5. Each is linked with GJA8 in more than 3 cancer types. Because this analysis shows association rather than direction, both GJA8-to-partner and partner-to-GJA8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GJA8 versus TCEA3 in GBM, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA8→partner) and Y-score (partner→GJA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TCEA3 →	+1.098	+1.484	.001	<.001	3	4
GBM	PEAK3 →	-0.494	-1.390	.006	.001	3	3
CCRCC	PLPPR5 →	+1.198	+0.548	<.001	<.001	3	2
UCEC	CXCL16 →	-1.755	-1.014	.007	.003	3	2
UCEC	RPL5P14 →	+1.458	+1.137	<.001	.002	3	2
LSCC	ACTR5 →	+0.406	+0.679	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,541 associations by consensus.

GJA8 vs TCEA3 — GBM

Explore this scatter interactively →