GJA8

Across TCGA cell cohorts, GJA8 RNA expression is significantly associated with the mutation status of many other genes, with 90 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GJA8-associated genes across cancer lineages are ZNF786, MAGEE1, and EPB41L3. Each is linked with GJA8 in more than 1 cancer types. Because this analysis shows association rather than direction, both GJA8-to-partner and partner-to-GJA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF786 grouped by GJA8-low versus GJA8-high in STOMACH.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA8→partner) and Y-score (partner→GJA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	ZNF786 →	+4.285	+0.015	.007	<.001	3	2
LUNG_NSCLC_LUAD	MAGEE1 →	+3.734	+0.594	.006	<.001	3	2
LUNG_NSCLC_LUAD	EPB41L3 →	+2.564	+0.299	.007	.006	3	2
BLOOD_Leukemia	SORCS1 →	+3.384	+0.007	.001	<.001	3	2
BLOOD_Lymphoma	CHL1 →	+3.544	+0.025	.001	<.001	3	2
BLOOD_Lymphoma	KAT6B →	+2.807	+0.017	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 90 associations by consensus.

ZNF786 by GJA8 expression — STOMACH

Explore this box plot interactively →