Across TCGA patient cohorts, GJA4 RNA expression is significantly associated with the RNA expression of many other genes, with 14,919 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible GJA4-associated genes across cancer lineages are MYCT1, USHBP1, and ESAM. Each is linked with GJA4 in more than 33 cancer types. Because this analysis shows association rather than direction, both GJA4-to-partner and partner-to-GJA4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA4→partner) and Y-score (partner→GJA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
MESO	MYCT1 →	+1.693	+1.722	<.001	<.001	3	34
KIRC	USHBP1 →	+1.167	+1.548	<.001	<.001	3	34
MESO	ESAM →	+1.889	+1.728	<.001	<.001	3	34
MESO	CDH5 →	+2.106	+1.735	<.001	<.001	3	33
KIRC	ENG →	+1.314	+1.608	<.001	<.001	3	33
CHOL	VWF →	+2.762	+1.354	<.001	.003	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,919 associations by consensus.

Exploration

GJA4 survival (RNA) · tumor vs normal (RNA) · all GJA4 data types