GJA3

Across TCGA patient cohorts, GJA3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,129 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GJA3-associated proteins across cancer lineages are SHANK3_S375, GPC1, and NAB2_S171. Each is linked with GJA3 in more than 3 cancer types. Because this analysis shows association rather than direction, both GJA3-to-partner and partner-to-GJA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GJA3 versus SHANK3_S375 in LUAD, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA3→partner) and Y-score (partner→GJA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SHANK3_S375 →	-0.667	-0.232	.003	.004	3	4
LSCC	GPC1 →	+0.712	+1.099	<.001	<.001	3	4
LSCC	NAB2_S171 →	+0.381	+0.962	<.001	<.001	3	3
HNSC	RPS25 →	+0.256	+0.656	.009	.006	3	3
LSCC	CRACDL_S490 →	-0.754	-0.860	<.001	.001	3	3
LSCC	EHBP1 →	+0.280	+0.949	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,129 associations by consensus.

GJA3 vs SHANK3_S375 — LUAD

Explore this scatter interactively →