GJA3

Across TCGA cell cohorts, GJA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,171 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GJA3-associated GO terms across cancer lineages are Gap junction-mediated intercellular transport, Cell communication involved in cardiac conduction, and Putrescine transport. Each is linked with GJA3 in more than 7 cancer types. Because this analysis shows association rather than direction, both GJA3-to-partner and partner-to-GJA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gap junction-mediated intercellular transport grouped by GJA3-low versus GJA3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA3→partner) and Y-score (partner→GJA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Gap junction-mediated intercellular transport →	+0.832	+1.253	<.001	<.001	3	8
LARGE_INTESTINE	Cell communication involved in cardiac conduction →	-0.177	-0.960	.003	.003	3	8
LUNG_SCLC	Putrescine transport →	-0.155	-0.554	<.001	.008	3	7
STOMACH	Reproductive structure development →	-0.072	-0.692	<.001	<.001	3	7
KIDNEY	Fructose 1,6-bisphosphate metabolic process →	+0.103	+0.648	.001	<.001	3	7
STOMACH	Positive regulation of mitotic cell cycle →	+0.099	+1.330	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,171 associations by consensus.

Gap junction-mediated intercellular transport by GJA3 expression — SOFT_TISSUE

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