GJA10

Across TCGA pan-cancer cohorts, GJA10 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GJA10 data layer compared with 18 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GJA10 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated GJA10 expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

UCEC, CCRCC, and LUAD are the cancer types where GJA10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.883	0.531	.017	14	view →
CCRCC	DFS	Median	All	0.976	0.852	.006	9	view →
LUAD	DFS	Median	III,IV	0.351	0.696	.014	9	view →
PDAC	DFS	Quartile	II,III,IV	0.208	0.444	.007	2	view →
GBM	OS	Tertile	All	0.439	0.269	.027	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

GJA10–UCEC (DFS)

Open the UCEC breakdown →