GJA10

Across TCGA patient cohorts, GJA10 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GJA10-associated genes across cancer lineages are INPP4B, PCNA, and VHL. Each is linked with GJA10 in more than 1 cancer types. Because this analysis shows association rather than direction, both GJA10-to-partner and partner-to-GJA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by GJA10-low versus GJA10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA10→partner) and Y-score (partner→GJA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.259	-1.401	.032	.046	3	2
UCEC	PCNA →	+0.291	+2.906	<.001	.001	3	2
UCEC	VHL →	-0.840	-2.115	<.001	.017	3	2
UCEC	ATM →	-0.485	-3.156	.004	.018	3	2
SKCM	CDK1 →	+0.204	+1.807	.004	.026	3	2
UCEC	C-Raf →	+0.151	+2.222	.004	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

INPP4B by GJA10 expression — UCEC

Explore this box plot interactively →