GJA10

Across TCGA cell cohorts, GJA10 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GJA10-associated genes across cancer lineages are CFC1B, CST2, and PRAMEF8. Each is linked with GJA10 in more than 1 cancer types. Because this analysis shows association rather than direction, both GJA10-to-partner and partner-to-GJA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFC1B grouped by GJA10-low versus GJA10-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GJA10→partner) and Y-score (partner→GJA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CFC1B →	+0.158	+3.736	<.001	.007	3	1
LUNG_SCLC	CST2 →	+0.053	+3.817	<.001	.004	3	1
LUNG_SCLC	PRAMEF8 →	+0.045	+3.523	<.001	.008	3	1
LUNG_SCLC	PRAMEF10 →	+0.708	+4.058	<.001	.007	3	1
LUNG_SCLC	PRAMEF17 →	+0.008	+4.058	<.001	.007	3	1
LUNG_SCLC	PRAMEF14 →	+0.248	+4.938	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

CFC1B by GJA10 expression — LUNG_SCLC

Explore this box plot interactively →