GIPR

Across TCGA patient cohorts, GIPR RNA expression is significantly associated with the protein abundance of many other proteins, with 15,219 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GIPR-associated proteins across cancer lineages are EML2, KIF23, and WDHD1. Each is linked with GIPR in more than 5 cancer types. Because this analysis shows association rather than direction, both GIPR-to-partner and partner-to-GIPR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GIPR versus EML2 in BRCA, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GIPR→partner) and Y-score (partner→GIPR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EML2 →	+0.526	+1.268	<.001	<.001	3	6
UCEC	KIF23 →	-0.549	-0.735	.001	.001	3	6
LUAD	WDHD1 →	-0.658	-0.516	.001	.007	3	5
LSCC	RFC4 →	-0.360	-0.389	.001	<.001	3	5
LSCC	STMN1 →	-0.557	-0.376	.005	.004	3	5
OV	AMPD3 →	+0.497	+0.547	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,219 associations by consensus.

GIPR vs EML2 — BRCA

Explore this scatter interactively →