GIPC2

Across TCGA patient cohorts, GIPC2 mutation is significantly associated with the RNA expression of many other genes, with 1,930 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GIPC2-associated genes across cancer lineages are LINC02107, RPS29P27, and ADM. Each is linked with GIPC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GIPC2-to-partner and partner-to-GIPC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02107 grouped by GIPC2-low versus GIPC2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIPC2→partner) and Y-score (partner→GIPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	LINC02107 →	+0.305	+4.506	<.001	<.001	3	2
BLCA	RPS29P27 →	+0.234	+7.640	<.001	.009	3	2
UCEC	ADM →	+0.961	+2.818	.001	<.001	3	1
UCEC	LIN7C →	+0.463	+2.230	.007	.006	3	1
UCEC	PGAP2 →	+0.340	+1.936	.008	.003	3	1
UCEC	PTPRJ →	+0.691	+2.831	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,930 associations by consensus.

LINC02107 by GIPC2 expression — LUSC

Explore this box plot interactively →