GIPC2

Across TCGA cell cohorts, GIPC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,702 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GIPC2-associated GO terms across cancer lineages are Cell-substrate junction organization, Sterol catabolic process, and Cholesterol catabolic process. Each is linked with GIPC2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GIPC2-to-partner and partner-to-GIPC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate junction organization grouped by GIPC2-low versus GIPC2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GIPC2→partner) and Y-score (partner→GIPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cell-substrate junction organization →	+0.121	+0.092	<.001	.003	3	7
URINARY_TRACT	Sterol catabolic process →	-0.287	-1.400	.005	.001	3	7
URINARY_TRACT	Cholesterol catabolic process →	-0.287	-1.400	.005	.001	3	7
PANCREAS	Sodium ion homeostasis →	+0.231	+1.297	<.001	<.001	3	7
SOFT_TISSUE	Protein transport into membrane raft →	+0.496	+0.294	.002	.005	3	7
LUNG_SCLC	Macrophage colony-stimulating factor signaling pathway →	+0.837	+0.999	.003	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,702 associations by consensus.

Cell-substrate junction organization by GIPC2 expression — BONE

Explore this box plot interactively →