GIPC1

Across TCGA patient cohorts, GIPC1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,617 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GIPC1-associated genes across cancer lineages are NECTIN4, LAD1, and B3GNT3. Each is linked with GIPC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GIPC1-to-partner and partner-to-GIPC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GIPC1 versus NECTIN4 in LSCC, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIPC1→partner) and Y-score (partner→GIPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NECTIN4 →	+1.401	+0.416	<.001	<.001	3	6
BRCA	LAD1 →	+1.156	+0.220	<.001	.002	3	6
UCEC	B3GNT3 →	+1.834	+0.413	<.001	<.001	3	6
UCEC	ANXA2 →	+1.004	+0.318	<.001	.005	3	6
HNSC	ELOVL1 →	+0.785	+0.407	<.001	<.001	3	6
UCEC	STX10 →	+0.717	+0.356	.008	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,617 associations by consensus.

GIPC1 vs NECTIN4 — LSCC

Explore this scatter interactively →