GINS4

Across TCGA patient cohorts, GINS4 protein abundance is significantly associated with the RNA expression of many other genes, with 17,195 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GINS4-associated genes across cancer lineages are CCNA2, GINS1, and CENPI. Each is linked with GINS4 in more than 8 cancer types. Because this analysis shows association rather than direction, both GINS4-to-partner and partner-to-GINS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GINS4 versus CCNA2 in OV, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GINS4→partner) and Y-score (partner→GINS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCNA2 →	+1.408	+0.751	<.001	<.001	3	9
LUAD	GINS1 →	+1.262	+0.821	<.001	<.001	3	8
LUAD	CENPI →	+1.238	+0.738	<.001	<.001	3	8
COAD	OIP5 →	+0.881	+0.675	.008	.008	3	8
OV	FBXO5 →	+1.079	+0.918	<.001	<.001	3	8
LUAD	TTK →	+1.251	+0.816	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,195 associations by consensus.

GINS4 vs CCNA2 — OV

Explore this scatter interactively →