GINS4

Across TCGA patient cohorts, GINS4 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GINS4-associated genes across cancer lineages are MSH6. Each is linked with GINS4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GINS4-to-partner and partner-to-GINS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSH6 grouped by GINS4-low versus GINS4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GINS4→partner) and Y-score (partner→GINS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MSH6 →	-0.528	-2.990	.002	.036	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MSH6 by GINS4 expression — UCEC

Explore this box plot interactively →