GINS2

Across TCGA patient cohorts, GINS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,974 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GINS2-associated proteins across cancer lineages are PRIM2, SMC2, and SMC4. Each is linked with GINS2 in more than 9 cancer types. Because this analysis shows association rather than direction, both GINS2-to-partner and partner-to-GINS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GINS2 versus PRIM2 in OV, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GINS2→partner) and Y-score (partner→GINS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PRIM2 →	+0.616	+1.266	<.001	<.001	3	10
GBM	SMC2 →	+0.792	+1.053	<.001	<.001	3	10
GBM	SMC4 →	+0.731	+1.054	<.001	<.001	3	10
HNSC	RRM1 →	+0.556	+0.993	<.001	<.001	3	10
OV	CDK1 →	+0.896	+1.159	<.001	<.001	3	10
GBM	DHFR →	+0.748	+0.968	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,974 associations by consensus.

GINS2 vs PRIM2 — OV

Explore this scatter interactively →