GIN1

Across TCGA patient cohorts, GIN1 mutation is significantly associated with the RNA expression of many other genes, with 2,678 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GIN1-associated genes across cancer lineages are LINC02745, FAM223B, and RNA5SP481. Each is linked with GIN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GIN1-to-partner and partner-to-GIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02745 grouped by GIN1-low versus GIN1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIN1→partner) and Y-score (partner→GIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LINC02745 →	+0.100	+4.270	.004	.003	3	2
BRCA	FAM223B →	+0.037	+4.920	<.001	.004	3	2
SKCM	RNA5SP481 →	+0.169	+4.475	<.001	.005	3	2
SKCM	RN7SKP56 →	+0.133	+4.339	<.001	<.001	3	2
SKCM	CDRT15P2 →	+0.072	+3.809	.003	.003	3	2
LUSC	MIR4470 →	+0.731	+3.206	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,678 associations by consensus.

LINC02745 by GIN1 expression — BRCA

Explore this box plot interactively →