Across TCGA cell cohorts, GIMAP1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GIMAP1-associated genes across cancer lineages are SPATA8, SLC22A8, and HTR1E. Each is linked with GIMAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GIMAP1-to-partner and partner-to-GIMAP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GIMAP1→partner) and Y-score (partner→GIMAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SPATA8 →	+0.280	+4.347	.005	.001	3	1
SKIN	SLC22A8 →	+0.015	+5.415	.006	.004	3	1
SKIN	HTR1E →	+0.036	+4.977	<.001	.007	3	1
SKIN	SI →	+0.006	+4.977	<.001	.007	3	1
BLOOD_Leukemia	TCF21 →	+0.019	+4.705	<.001	.003	3	1
BLOOD_Leukemia	NXPE4 →	+0.020	+4.276	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

GIMAP1 survival (RNA) · tumor vs normal (RNA) · all GIMAP1 data types