GIGYF1

Across TCGA patient cohorts, GIGYF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,613 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GIGYF1-associated proteins across cancer lineages are MEPCE, HNRNPU, and SMC1A. Each is linked with GIGYF1 in more than 8 cancer types. Because this analysis shows association rather than direction, both GIGYF1-to-partner and partner-to-GIGYF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GIGYF1 versus MEPCE in LSCC, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GIGYF1→partner) and Y-score (partner→GIGYF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MEPCE →	+0.337	+0.651	<.001	<.001	3	9
GBM	HNRNPU →	+0.292	+0.492	<.001	<.001	3	7
GBM	SMC1A →	+0.267	+0.371	<.001	<.001	3	7
GBM	SMC3 →	+0.242	+0.317	<.001	<.001	3	7
GBM	GTF2I →	+0.444	+0.496	<.001	<.001	3	7
HNSC	PUS7 →	+0.606	+0.605	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,613 associations by consensus.

GIGYF1 vs MEPCE — LSCC

Explore this scatter interactively →