GIGYF1

Across TCGA cell cohorts, GIGYF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,437 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GIGYF1-associated GO terms across cancer lineages are Pre-mRNA catabolic process, RNA catabolic process, and Negative regulation of translational initiation. Each is linked with GIGYF1 in more than 19 cancer types. Because this analysis shows association rather than direction, both GIGYF1-to-partner and partner-to-GIGYF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by GIGYF1-low versus GIGYF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GIGYF1→partner) and Y-score (partner→GIGYF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.271	+1.787	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	RNA catabolic process →	+0.078	+1.614	<.001	<.001	3	18
BONE	Negative regulation of translational initiation →	+0.119	+1.388	<.001	<.001	3	17
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.095	+1.210	<.001	<.001	3	17
BONE	Positive regulation of DNA recombination →	+0.114	+1.662	.003	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.174	-1.681	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,437 associations by consensus.

Pre-mRNA catabolic process by GIGYF1 expression — BONE

Explore this box plot interactively →