GID8

Across TCGA patient cohorts, GID8 mutation is significantly associated with the RNA expression of many other genes, with 517 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GID8-associated genes across cancer lineages are RN7SL248P, RPS29P9, and IGHD1-26. Each is linked with GID8 in more than 2 cancer types. Because this analysis shows association rather than direction, both GID8-to-partner and partner-to-GID8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by GID8-low versus GID8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GID8→partner) and Y-score (partner→GID8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.069	+3.219	<.001	.004	3	3
SKCM	RPS29P9 →	+0.263	+4.440	.002	.006	3	2
UCEC	IGHD1-26 →	+0.487	+2.484	<.001	.007	3	2
UCEC	RNU6-1156P →	+0.400	+1.971	<.001	.009	3	2
UCEC	RNA5SP146 →	+0.226	+2.302	<.001	.003	3	2
SKCM	PMS2P11 →	+0.123	+4.661	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 517 associations by consensus.

RN7SL248P by GID8 expression — UCEC

Explore this box plot interactively →