GHSR

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GHSR RNA expression is significantly associated with the protein abundance of many other proteins, with 4,229 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GHSR-associated proteins across cancer lineages are LMNB2, CENPF_S3023, and CKAP2. Each is linked with GHSR in more than 2 cancer types. Because this analysis shows association rather than direction, both GHSR-to-partner and partner-to-GHSR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GHSR versus LMNB2 in OV, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GHSR→partner) and Y-score (partner→GHSR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVLMNB2 →-0.280-0.041.002.00333
LUADCENPF_S3023 →+1.522+0.179<.001<.00132
LUADCKAP2 →+0.525+0.107<.001.00132
LUADDCP1A_T430 →+0.983+0.400.008.00132
GBMZBTB20_S353 →-0.548-0.180<.001.00732
OVPDIA4 →+0.333+0.047.005.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,229 associations by consensus.

GHSR vs LMNB2 — OV

Per-sample scatter of GHSR vs LMNB2 in OV (Pearson r = -0.32).

Explore this scatter interactively →

Exploration