GHRL

Across TCGA cell cohorts, GHRL RNA expression is significantly associated with the go_rna of many other GO terms, with 2,691 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GHRL-associated GO terms across cancer lineages are Positive regulation of circadian sleep/wake cycle, non-REM sleep, Positive regulation of growth rate, and Adult feeding behavior. Each is linked with GHRL in more than 16 cancer types. Because this analysis shows association rather than direction, both GHRL-to-partner and partner-to-GHRL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of circadian sleep/wake cycle, non-REM sleep grouped by GHRL-low versus GHRL-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GHRL→partner) and Y-score (partner→GHRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of circadian sleep/wake cycle, non-REM sleep →	+0.482	+0.986	<.001	<.001	3	17
BREAST	Positive regulation of growth rate →	-0.200	-0.252	.006	.001	3	14
CNS	Adult feeding behavior →	+0.239	+0.204	.009	<.001	2	13
BLOOD_Leukemia	Regulation of circadian sleep/wake cycle, REM sleep →	+0.318	+0.950	<.001	<.001	3	11
OESOPHAGUS	Positive regulation of bone development →	-0.979	-0.213	<.001	.004	3	10
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.100	+0.346	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,691 associations by consensus.

Positive regulation of circadian sleep/wake cycle, non-REM sleep by GHRL expression — BLOOD_Leukemia

Explore this box plot interactively →