GHRH

Across TCGA patient cohorts, GHRH RNA expression is significantly associated with the go_rna of many other GO terms, with 6,872 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GHRH-associated GO terms across cancer lineages are Mitochondrial translation, Aerobic respiration, and Proton motive force-driven ATP synthesis. Each is linked with GHRH in more than 15 cancer types. Because this analysis shows association rather than direction, both GHRH-to-partner and partner-to-GHRH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translation grouped by GHRH-low versus GHRH-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GHRH→partner) and Y-score (partner→GHRH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial translation →	+0.104	+0.368	<.001	<.001	3	16
STAD	Aerobic respiration →	+0.058	+0.274	<.001	<.001	3	15
STAD	Proton motive force-driven ATP synthesis →	+0.111	+0.339	<.001	<.001	2	15
STAD	Mitochondrial gene expression →	+0.099	+0.344	<.001	<.001	3	13
ESCA	Nucleoside triphosphate biosynthetic process →	+0.058	+0.812	<.001	.006	2	14
STAD	NADH dehydrogenase complex assembly →	+0.100	+0.349	<.001	<.001	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,872 associations by consensus.

Mitochondrial translation by GHRH expression — STAD

Explore this box plot interactively →