GHRH

Across TCGA patient cohorts, GHRH mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GHRH-associated genes across cancer lineages are HSC, Th2 cells, and Megakaryocytes. Each is linked with GHRH in more than 1 cancer types. Because this analysis shows association rather than direction, both GHRH-to-partner and partner-to-GHRH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSC grouped by GHRH-low versus GHRH-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GHRH→partner) and Y-score (partner→GHRH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HSC →	+0.134	+3.191	.019	.009	3	1
UCEC	Th2 cells →	+0.233	+2.818	.013	.035	3	1
UCEC	Megakaryocytes →	+0.030	+3.024	.019	.019	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

HSC by GHRH expression — UCEC

Explore this box plot interactively →