GHRH

Across TCGA cell cohorts, GHRH RNA expression is significantly associated with the go_rna of many other GO terms, with 815 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GHRH-associated GO terms across cancer lineages are Carbon dioxide transport, Negative regulation of telomere maintenance via telomere lengthening, and Negative regulation of dendritic cell antigen processing and presentation. Each is linked with GHRH in more than 3 cancer types. Because this analysis shows association rather than direction, both GHRH-to-partner and partner-to-GHRH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Carbon dioxide transport grouped by GHRH-low versus GHRH-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GHRH→partner) and Y-score (partner→GHRH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Carbon dioxide transport →	+0.994	+0.102	<.001	.007	3	4
BLOOD_Lymphoma	Negative regulation of telomere maintenance via telomere lengthening →	+0.056	+0.052	<.001	.007	3	3
LUNG_SCLC	Negative regulation of dendritic cell antigen processing and presentation →	-0.907	-3.009	.001	.003	3	3
LUNG_SCLC	Regulation of angiogenesis →	-0.045	-3.202	<.001	.001	3	3
BLOOD_Leukemia	Negative regulation of norepinephrine secretion →	+1.002	+0.151	<.001	.002	3	3
LUNG_SCLC	Negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II →	-0.619	-2.118	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 815 associations by consensus.

Carbon dioxide transport by GHRH expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →