GHITM

Across TCGA cell cohorts, GHITM RNA expression is significantly associated with the go_rna of many other GO terms, with 3,513 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GHITM-associated GO terms across cancer lineages are L-aspartate biosynthetic process, Response to transition metal nanoparticle, and Positive regulation of mitochondrial RNA catabolic process. Each is linked with GHITM in more than 15 cancer types. Because this analysis shows association rather than direction, both GHITM-to-partner and partner-to-GHITM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-aspartate biosynthetic process grouped by GHITM-low versus GHITM-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GHITM→partner) and Y-score (partner→GHITM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	L-aspartate biosynthetic process →	+0.177	+0.414	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Response to transition metal nanoparticle →	+0.274	+0.861	<.001	<.001	3	13
LUNG_SCLC	Positive regulation of mitochondrial RNA catabolic process →	+0.103	+0.502	<.001	.001	3	12
STOMACH	L-glutamate biosynthetic process →	+0.240	+0.832	.004	.005	3	12
KIDNEY	Glucosamine metabolic process →	+0.126	+0.603	.001	<.001	3	10
LUNG_NSCLC_LUAD	Regulation of mitochondrial RNA catabolic process →	+0.106	+0.730	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,513 associations by consensus.

L-aspartate biosynthetic process by GHITM expression — SKIN

Explore this box plot interactively →