GHDC

Across TCGA patient cohorts, GHDC RNA expression is significantly associated with the protein abundance of many other proteins, with 11,461 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GHDC-associated proteins across cancer lineages are PIP4K2B, HBP1, and ESD. Each is linked with GHDC in more than 4 cancer types. Because this analysis shows association rather than direction, both GHDC-to-partner and partner-to-GHDC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GHDC versus PIP4K2B in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GHDC→partner) and Y-score (partner→GHDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PIP4K2B →	+0.350	+0.746	<.001	<.001	3	5
HNSC	HBP1 →	+0.573	+0.648	.001	.001	3	5
OV	ESD →	+0.512	+0.708	<.001	<.001	3	4
BRCA	TOM1L1 →	+0.458	+0.682	<.001	<.001	3	4
BRCA	PTER →	+0.552	+0.944	<.001	<.001	3	4
BRCA	C11orf54 →	+0.407	+0.578	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,461 associations by consensus.

GHDC vs PIP4K2B — BRCA

Explore this scatter interactively →