GH2

Across TCGA patient cohorts, GH2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,214 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GH2-associated genes across cancer lineages are YWHAE, CRK, and INPP5K. Each is linked with GH2 in more than 8 cancer types. Because this analysis shows association rather than direction, both GH2-to-partner and partner-to-GH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GH2 versus YWHAE in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GH2→partner) and Y-score (partner→GH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	YWHAE →	+0.857	+0.272	.002	<.001	3	9
OV	CRK →	+0.640	+0.440	<.001	<.001	3	9
COAD	INPP5K →	+0.544	+0.232	<.001	<.001	3	8
BRCA	RABEP1 →	+0.922	+0.253	<.001	<.001	3	8
OV	NUP88 →	+0.557	+0.286	<.001	.002	3	7
LSCC	FXR2 →	+0.530	+0.207	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,214 associations by consensus.

GH2 vs YWHAE — HNSC

Explore this scatter interactively →