GH1

Across TCGA patient cohorts, GH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,047 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GH1-associated GO terms across cancer lineages are Negative regulation of lymphocyte apoptotic process, Notch signaling pathway, and T cell apoptotic process. Each is linked with GH1 in more than 20 cancer types. Because this analysis shows association rather than direction, both GH1-to-partner and partner-to-GH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of lymphocyte apoptotic process grouped by GH1-low versus GH1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GH1→partner) and Y-score (partner→GH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of lymphocyte apoptotic process →	+0.064	+0.138	<.001	<.001	3	21
STAD	Notch signaling pathway →	+0.043	+0.110	<.001	<.001	3	21
STAD	T cell apoptotic process →	+0.054	+0.131	<.001	<.001	3	20
STAD	Regulation of T cell apoptotic process →	+0.055	+0.127	<.001	<.001	3	20
STAD	Regulation of lymphocyte differentiation →	+0.056	+0.129	<.001	<.001	3	20
STAD	Negative regulation of leukocyte apoptotic process →	+0.074	+0.148	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,047 associations by consensus.

Negative regulation of lymphocyte apoptotic process by GH1 expression — STAD

Explore this box plot interactively →