GGTLC3

Across TCGA cell cohorts, GGTLC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 752 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible GGTLC3-associated GO terms across cancer lineages are Phosphatidylinositol 3-kinase/protein kinase B signal transduction, Activation of NF-kappaB-inducing kinase activity, and Peptidyl-lysine oxidation. Each is linked with GGTLC3 in more than 3 cancer types. Because this analysis shows association rather than direction, both GGTLC3-to-partner and partner-to-GGTLC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol 3-kinase/protein kinase B signal transduction grouped by GGTLC3-low versus GGTLC3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGTLC3→partner) and Y-score (partner→GGTLC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Phosphatidylinositol 3-kinase/protein kinase B signal transduction →	+0.092	+0.296	<.001	.001	3	4
OVARY	Activation of NF-kappaB-inducing kinase activity →	-0.119	-0.251	<.001	.006	3	4
OVARY	Peptidyl-lysine oxidation →	-0.748	-0.244	.002	.007	3	4
KIDNEY	Nephric duct formation →	+1.150	+0.041	<.001	<.001	3	3
SOFT_TISSUE	Cholesterol biosynthetic process →	+0.111	+0.051	.001	.008	3	3
OVARY	Sterol biosynthetic process →	+0.108	+0.284	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 752 associations by consensus.

Phosphatidylinositol 3-kinase/protein kinase B signal transduction by GGTLC3 expression — OVARY

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