GGTLC2

Across TCGA patient cohorts, GGTLC2 protein abundance is significantly associated with the RNA expression of many other genes, with 210 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GGTLC2-associated genes across cancer lineages are ATRNL1, CNN3, and DEFB126. Each is linked with GGTLC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GGTLC2-to-partner and partner-to-GGTLC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGTLC2 versus ATRNL1 in UCEC, with a Pearson correlation of -0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGTLC2→partner) and Y-score (partner→GGTLC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATRNL1 →	-1.700	-0.716	.009	.002	3	1
UCEC	CNN3 →	-0.715	-0.799	.006	.004	3	1
UCEC	DEFB126 →	+1.523	+0.676	.002	.004	3	1
UCEC	CHL1 →	-2.481	-0.900	.001	.004	3	1
UCEC	TSPAN2 →	-2.323	-0.830	.002	.004	3	1
UCEC	GATA6 →	-1.026	-0.750	.005	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 210 associations by consensus.

GGTLC2 vs ATRNL1 — UCEC

Explore this scatter interactively →