GGTLC2

Across TCGA cell cohorts, GGTLC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 743 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GGTLC2-associated GO terms across cancer lineages are Growth hormone receptor signaling pathway via JAK-STAT, Protein localization to extracellular region, and Protein secretion. Each is linked with GGTLC2 in more than 3 cancer types. Because this analysis shows association rather than direction, both GGTLC2-to-partner and partner-to-GGTLC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Growth hormone receptor signaling pathway via JAK-STAT grouped by GGTLC2-low versus GGTLC2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGTLC2→partner) and Y-score (partner→GGTLC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Growth hormone receptor signaling pathway via JAK-STAT →	+0.099	+0.033	.008	.004	3	4
UPPER_AERODIGESTIVE_TRACT	Protein localization to extracellular region →	+0.046	+0.075	.009	.007	3	3
UPPER_AERODIGESTIVE_TRACT	Protein secretion →	+0.050	+0.072	.006	.009	3	3
UPPER_AERODIGESTIVE_TRACT	Intrinsic apoptotic signaling pathway →	+0.044	+0.128	<.001	.007	3	3
UPPER_AERODIGESTIVE_TRACT	Respiratory electron transport chain →	+0.067	+0.130	.003	.008	3	3
BLOOD_Lymphoma	Response to topologically incorrect protein →	+0.055	+0.037	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 743 associations by consensus.

Growth hormone receptor signaling pathway via JAK-STAT by GGTLC2 expression — BLOOD_Lymphoma

Explore this box plot interactively →