GGT6

Across TCGA cell cohorts, GGT6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,307 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GGT6-associated GO terms across cancer lineages are T cell mediated immunity, Cell-cell adhesion mediated by cadherin, and Nuclear-transcribed mRNA catabolic process, deadenylation-independent decay. Each is linked with GGT6 in more than 8 cancer types. Because this analysis shows association rather than direction, both GGT6-to-partner and partner-to-GGT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T cell mediated immunity grouped by GGT6-low versus GGT6-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGT6→partner) and Y-score (partner→GGT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	T cell mediated immunity →	+0.217	+2.147	.001	.003	3	9
STOMACH	Cell-cell adhesion mediated by cadherin →	+0.201	+2.118	.002	.003	3	9
OESOPHAGUS	Nuclear-transcribed mRNA catabolic process, deadenylation-independent decay →	+0.229	+2.738	<.001	<.001	3	9
LARGE_INTESTINE	Positive regulation of vitamin D receptor signaling pathway →	+0.235	+3.078	<.001	<.001	3	8
OVARY	Positive regulation of brown fat cell differentiation →	+0.110	+2.220	<.001	<.001	3	8
STOMACH	Cellular response to alcohol →	+0.141	+2.658	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,307 associations by consensus.

T cell mediated immunity by GGT6 expression — URINARY_TRACT

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