GGT6

Across TCGA cell cohorts, GGT6 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GGT6-associated genes across cancer lineages are MRGPRG, ODF1, and CDX4. Each is linked with GGT6 in more than 1 cancer types. Because this analysis shows association rather than direction, both GGT6-to-partner and partner-to-GGT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRGPRG grouped by GGT6-low versus GGT6-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGT6→partner) and Y-score (partner→GGT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MRGPRG →	+0.333	+4.930	<.001	.008	3	1
SKIN	ODF1 →	+0.026	+6.022	<.001	.001	3	1
LARGE_INTESTINE	CDX4 →	+0.011	+4.217	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MRGPRG by GGT6 expression — SOFT_TISSUE

Explore this box plot interactively →