Q-omics provides the consensus-scored GGT4P profile across patient tissues and cancer cell-line models. GGT4P expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, GGT4P is differentially expressed in 7, with the highest sampling consensus in KICH. Additionally, GGT4P RNA expression shows 11,306 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight ACC, KICH, and TGCT as cancer lineages where GGT4P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GGT4P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GGT4P survival associations across molecular data types. GGT4P RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GGT4P RNA expression–survival associations across cancer types. High GGT4P expression shows unfavorable associations in ACC, UVM and LIHC, but favorable associations in KIRP, MESO and SKCM. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for GGT4P RNA expression.
This table summarizes GGT4P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for GGT4P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GGT4P shows lower tumor expression in KICH and higher tumor expression in HNSC, KIRC, THCA, COAD and LUAD. The KICH box plot shows higher GGT4P RNA expression in normal versus tumor tissue (log2 FC = −1.176, t-test p < 0.001).
This table shows molecular features associated with GGT4P in patient tissues and cancer cell lines. In patient samples, GGT4P shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
