GGT2

Across TCGA patient cohorts, GGT2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,231 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GGT2-associated genes across cancer lineages are GGT1, CCNB1IP1, and SLC25A15. Each is linked with GGT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GGT2-to-partner and partner-to-GGT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGT2 versus GGT1 in PDAC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGT2→partner) and Y-score (partner→GGT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	GGT1 →	+0.451	+0.874	.009	.001	3	1
PDAC	CCNB1IP1 →	-0.318	-0.751	<.001	<.001	3	1
PDAC	SLC25A15 →	+0.491	+0.575	.002	.007	3	1
PDAC	SLC1A5 →	-0.675	-0.918	<.001	<.001	3	1
PDAC	FOXRED1 →	-0.196	-0.603	.008	.006	3	1
PDAC	PHACTR1 →	+0.318	+0.653	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,231 associations by consensus.

GGT2 vs GGT1 — PDAC

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