GGT2

Across TCGA pan-cancer cohorts, GGT2 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated GGT2 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher GGT2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GGT2 expression acts as an unfavorable survival marker, although some lineages such as KIRP and BLCA show a favorable association.

LIHC, KIRP, and OV are the cancer types where GGT2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.618	0.752	<.001	96	view →
KIRP	OS	Tertile	II,III,IV	0.919	0.692	.004	41	view →
OV	OS	Tertile	All	0.619	0.713	.002	38	view →
BLCA	OS	Quartile	All	0.701	0.539	.006	28	view →
LUAD	OS	Quartile	All	0.411	0.273	.007	22	view →
PAAD	OS	Quartile	All	0.232	0.464	.007	21	view →
BRCA	OS	Quartile	IV	0.217	0.820	.008	19	view →
UCS	OS	Tertile	All	0.544	0.768	.028	16	view →
THYM	DFS	Tertile	All	1.000	0.715	.019	12	view →
HNSC	OS	Median	III,IV	0.476	0.210	.016	11	view →
THCA	OS	Median	All	0.979	0.901	.014	10	view →
UVM	OS	Tertile	III,IV	0.136	0.874	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

GGT2–LIHC (OS)

Open the LIHC breakdown →