GGT2

Across TCGA patient cohorts, GGT2 protein abundance is significantly associated with the protein abundance of many other proteins, with 8,035 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GGT2-associated proteins across cancer lineages are ATP5MG, ATP7A_T152, and ATRX_S675. Each is linked with GGT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GGT2-to-partner and partner-to-GGT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGT2 versus ATP5MG in PDAC, with a Pearson correlation of 0.51.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GGT2→partner) and Y-score (partner→GGT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ATP5MG →	+0.468	+0.624	<.001	<.001	3	1
PDAC	ATP7A_T152 →	+0.539	+0.703	<.001	<.001	3	1
PDAC	ATRX_S675 →	+0.288	+0.575	<.001	<.001	3	1
PDAC	ATXN2_S728 →	-1.111	-0.793	<.001	<.001	3	1
PDAC	ATXN2L_S32 →	-0.671	-0.714	<.001	<.001	3	1
PDAC	BAZ1B_S189 →	+0.569	+0.643	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,035 associations by consensus.

GGT2 vs ATP5MG — PDAC

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