GGPS1

Across TCGA patient cohorts, GGPS1 mutation is significantly associated with the RNA expression of many other genes, with 2,974 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GGPS1-associated genes across cancer lineages are RNA5SP113, CDRT15P8, and NOCT. Each is linked with GGPS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GGPS1-to-partner and partner-to-GGPS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP113 grouped by GGPS1-low versus GGPS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGPS1→partner) and Y-score (partner→GGPS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP113 →	+0.451	+2.978	<.001	.001	3	3
READ	CDRT15P8 →	+0.125	+5.421	<.001	.005	3	2
UCEC	NOCT →	+0.707	+3.008	<.001	<.001	3	2
COAD	ATP5F1A →	+0.631	+3.499	<.001	.002	3	2
UCEC	HAUS1 →	+0.479	+2.280	.006	.001	3	2
UCEC	ABHD3 →	+0.632	+1.858	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,974 associations by consensus.

RNA5SP113 by GGPS1 expression — UCEC

Explore this box plot interactively →