GGN

Across TCGA pan-cancer cohorts, GGN Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated GGN data layer compared with 24 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher GGN Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GGN expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

LIHC, LGG, and ESCA are the cancer types where GGN Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.098	0.774	.001	21	view →
LGG	DFS	Median	All	0.110	0.833	<.001	6	view →
ESCA	OS	Median	II,III,IV	0.248	0.686	.025	6	view →
UCEC	DFS	Median	All	1.000	0.635	.029	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →
SKCM	DFS	Median	II,III,IV	1.000	0.681	.022	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

GGN–LIHC (OS)

Open the LIHC breakdown →