GGH

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GGH RNA expression is significantly associated with the protein abundance of many other proteins, with 17,174 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GGH-associated proteins across cancer lineages are MCM6, WDHD1, and RIF1. Each is linked with GGH in more than 7 cancer types. Because this analysis shows association rather than direction, both GGH-to-partner and partner-to-GGH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGH versus MCM6 in LUAD, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GGH→partner) and Y-score (partner→GGH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADMCM6 →+0.688+0.779<.001<.00138
LSCCWDHD1 →+0.673+0.723<.001<.00137
BRCARIF1 →+0.436+0.701<.001<.00137
LUADRRM2 →+0.706+0.891<.001<.00137
OVATAD2 →+0.467+0.938<.001.00237
OVSMC4 →+0.579+1.424<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,174 associations by consensus.

GGH vs MCM6 — LUAD

Per-sample scatter of GGH vs MCM6 in LUAD (Pearson r = 0.51).

Explore this scatter interactively →

Exploration